Gut microbiota diversity and atopic disease: does breast-feeding play a role?
نویسندگان
چکیده
Given how infrequent this observation has been in our cohort of patients, we propose that a large-scale study with a nested casecontrol design would be necessary to determine whether this clinical observation is representative of a true association. Unfortunately, such a study would be expensive and difficult to carry out, especially because AERD itself is so rare and patients with AERD having gastrointestinal complaints during desensitization are thought to represent less than a quarter of the total number of patients. Therefore, for events with a low frequency of occurrence, such as this, awareness of possible adverse drug reactions in a given cohort of patients and the increase in clinical suspicion that generally follows become even more powerful not only to further validate the underlying association that might have been missed but also to avoid unnecessary morbidity. Flavia C. L. Hoyte, MD Rohit K. Katial, MD
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عنوان ژورنال:
- The Journal of allergy and clinical immunology
دوره 131 1 شماره
صفحات -
تاریخ انتشار 2013